|
Mood Disorders
|
|
0.100 |
GeneticVariation
|
BEFREE |
Preliminary evidence suggests that BDNF (brain derived neurotrophic factor) rs6265 genetic polymorphism, BDNF gene promotor methylation and BDNF serum levels might play an important role in the pathogenesis of affective disorders.
|
30929061 |
2020 |
|
Depressive Symptoms
|
|
0.100 |
GeneticVariation
|
BEFREE |
Thus, we assessed whether the functional single nucleotide polymorphism (SNP) on the BDNF gene, Val66Met, moderated the relationship between depressive symptoms and perceived social support and unsupportive relationships, and whether these associations differed by gender.
|
31364951 |
2020 |
|
Depressive Symptoms
|
|
0.100 |
GeneticVariation
|
BEFREE |
BDNF (rs6265) and CRY1 (rs2287161) variants have been associated with more depressive symptoms in people with PD.
|
31292011 |
2020 |
|
Mental Depression
|
|
0.100 |
GeneticVariation
|
BEFREE |
The association between BDNF Val66Met and SI was modeled using logistic regression adjusted for age and sex, and in secondary analyses also for depression.
|
30329132 |
2020 |
|
Parkinson Disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
BDNF (rs6265) and CRY1 (rs2287161) variants have been associated with more depressive symptoms in people with PD.
|
31292011 |
2020 |
|
Depressed mood
|
|
0.100 |
GeneticVariation
|
BEFREE |
The association between BDNF Val66Met and SI was modeled using logistic regression adjusted for age and sex, and in secondary analyses also for depression.
|
30329132 |
2020 |
|
Impaired cognition
|
|
0.100 |
GeneticVariation
|
BEFREE |
Carriage of BDNF Val66Met has been associated with faster cognitive decline and greater hippocampal atrophy in cognitively normal elderly.
|
31771052 |
2020 |
|
Obsessive-Compulsive Disorder
|
|
0.100 |
GeneticVariation
|
BEFREE |
Here we studied the association of BDNF polymorphisms rs6265 and rs2883187 with OCD and its clinical characteristics in Iranian patients as well as the fluvoxamine-treatment outcome of OCD patients.
|
31180700 |
2020 |
|
Depressive disorder
|
|
0.100 |
GeneticVariation
|
BEFREE |
The association between BDNF Val66Met and SI was modeled using logistic regression adjusted for age and sex, and in secondary analyses also for depression.
|
30329132 |
2020 |
|
Mental deterioration
|
|
0.080 |
GeneticVariation
|
BEFREE |
Carriage of BDNF Val66Met has been associated with faster cognitive decline and greater hippocampal atrophy in cognitively normal elderly.
|
31771052 |
2020 |
|
Mild cognitive disorder
|
|
0.070 |
GeneticVariation
|
BEFREE |
Impact of APOE and BDNF Val66Met Gene Polymorphisms on Cognitive Functions in Patients with Amnestic Mild Cognitive Impairment.
|
31771052 |
2020 |
|
Mixed anxiety and depressive disorder
|
|
0.030 |
GeneticVariation
|
BEFREE |
The BDNF Val66Met polymorphism alters susceptibility to depression, anxiety, and insomnia by altering availability and expression of BDNF in brain and blood.
|
31782101 |
2020 |
|
Sleeplessness
|
|
0.030 |
GeneticVariation
|
BEFREE |
The BDNF Val66Met polymorphism alters susceptibility to depression, anxiety, and insomnia by altering availability and expression of BDNF in brain and blood.
|
31782101 |
2020 |
|
Premenstrual Dysphoric Disorder
|
|
0.020 |
GeneticVariation
|
BEFREE |
Epigenetic intersection of BDNF Val66Met genotype with premenstrual dysphoric disorder transcriptome in a cross-species model of estradiol add-back.
|
30356121 |
2020 |
|
Sleep Apnea, Central
|
|
0.010 |
GeneticVariation
|
BEFREE |
This study aims to examine <i>COMT</i> Val158Met (rs4680) and <i>BDNF</i> Val66Met (rs6265) polymorphisms in CSA.
|
31142902 |
2020 |
|
Conduct Disorder
|
|
0.010 |
GeneticVariation
|
BEFREE |
Effects of BDNF Val66Met polymorphisms on brain structures and behaviors in adolescents with conduct disorder.
|
31264106 |
2020 |
|
Neurodevelopmental Disorders
|
|
0.010 |
GeneticVariation
|
BEFREE |
The Val66Met polymorphism of brain-derived neurotrophic factor (BDNF) has emerged as a high-interest genetic variant due to its importance in cortical maturation, and several studies have implicated its involvement in neurodevelopmental disorders.
|
31264106 |
2020 |
|
Cockayne Syndrome, Type I
|
|
0.010 |
GeneticVariation
|
BEFREE |
This study aims to examine <i>COMT</i> Val158Met (rs4680) and <i>BDNF</i> Val66Met (rs6265) polymorphisms in CSA.
|
31142902 |
2020 |
|
Body mass index
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Genetic analyses of diverse populations improves discovery for complex traits.
|
31217584 |
2019 |
|
Waist-Hip Ratio
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry.
|
30239722 |
2019 |
|
Body mass index
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
|
30595370 |
2019 |
|
Smoking
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences.
|
30643258 |
2019 |
|
Body mass index
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry.
|
30239722 |
2019 |
|
Psychotic Disorders
|
|
0.100 |
GeneticVariation
|
BEFREE |
Chronic methamphetamine interacts with BDNF Val66Met to remodel psychosis pathways in the mesocorticolimbic proteome.
|
31822818 |
2019 |
|
Impaired cognition
|
|
0.100 |
GeneticVariation
|
BEFREE |
Our analyses suggested the G196A (Val66Met) polymorphism was significantly associated with cog</span>nitive impairment in PD, especially in Caucasian populations.
|
31365694 |
2019 |